Primary Antibodies

bcl-2αAb-1 (Clone 100/D5) Mouse Monoclonal Antibody

Expression of Bcl-2α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2α protein, whereas the normal or hyperplastic germinal centers are negative.

Overview

Host: Mouse

Clone: 100/D5

Isotope: IgG1/ k

Species Reactivity: Human. Others not known

Epitope: aa 41-54

Immunogen: A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein

Molecular Weight: 25-26kDa

Positive Control: Tonsil or follicular lymphomas

Localization: Cytoplasm

Application: IHC, WB, IF, IP, FC

Purification Method: Protein G chromatography