Primary Antibodies

Thrombospondin (TSP) Ab-3 (Clone C6.7)

Thrombospondin is a protein from platelet a-granules. It is made up of three identical subunits bound by interchain disulfides. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.

Overview

Host: Mouse

Clone: C6.7

Isotope: IgG1

Species Reactivity: Human, Cow, Pig, Horse, Dog, Sheep, and Rat. Others-notknown

Epitope: platelet-or cell-binding domain at the extreme C-terminus of TSP.

Immunogen: a2+-replete, native purified human TSP from supernatant of thrombin-activatedplatelets

Molecular Weight: 450kDa (Non-reduced)

Localization: ecretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix

Application: WB, IP, IF, FC

Purification Method: Protein G chromatography